Identifying physical principles of spatiotemporal self-organization in living cells and tissues requires quantitative measurements of key physical quantities. Currently, progress is limited by our ability to perform accurate measurements of physical quantities in a controlled and minimally invasive way within living systems. The development of new measurement techniques will bring our understanding of the physical basis of life to a new level.
Our aim
Our aim is to develop technologies, or extend existing ones, that enable measurements of physical quantities that cannot currently be measured inside intact living systems. This includes electrical fields, material properties, mechanical stresses, osmotic and hydrostatic pressures, and flows of matter and energy. Additionally, we will develop smart robotic microscopy methods and AI-based approaches to perform high-throughput measurements of distributions of fluctuating physical quantities in intact cells, tissues and organisms.
Quantifying Rates and Flows in Living Matter
RESEARCH TOPIC 1
Mechanical and Electrical Measurements Across Scales
RESEARCH TOPIC 2
Revealing Energetics in Space and Time
RESEARCH TOPIC 3
A Robotic Lab for Generating Large Datasets
RESEARCH TOPIC 4
RA Leading Team
Elias Barriga
Elisabeth Fischer-Friedrich
Stephan W. Grill
Carsten Werner
PoL Groups
Ellen Adams
Elias Barriga
Jan Brugués
Otger Campàs
Stefan Diez
Miki Ebisuya
Elisabeth Fischer-Friedrich
Stephan W. Grill
Rita Mateus
Ivo F. Sbalzarini
Carsten Werner
Xingbo Yang
PoL Associates
Sebastian Aland
Michael Brand
Oliver Bruns
Jürgen Czarske
Christian Dahmann
Michael Schlierf
Pavel Tomancak
Jesse Veenvliet
Michael Weber
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Our work is driven by a sparkling collaborative atmosphere in Dresden between University and non-University research laboratories.